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Table 1 Hospitalized patient clinical and demographic characteristics by IRIS and study period

From: Hospital days attributable to immune reconstitution inflammatory syndrome in persons living with HIV before and after the 2012 DHHS HIV guidelines

  Total study duration n (%) Subjects with Time Period 1 non IRIS-attributable hospitalization n (%) Subjects with Time Period 1 IRIS-attributable hospitalization n (%) p value Subjects with Time Period 2 non IRIS-attributable hospitalization n (%) Subjects with Time Period 2 IRIS-attributable hospitalization n (%) p value
Total subjects 278 151 9   112 6  
Mean age 47.5 47.7 42.8 0.17 47.7 47.3 0.94
Sexa     0.73    0.66
 Male 192 (69) 105 (70) 7 (78)   75 (67) 5 (83)  
 Female 86 (31) 46 (30) 2 (22)   37 (33) 1 (17)  
Race/ethnicity     0.08    0.008
 White 121 (44) 61 (40) 2 (22)   58 (52) 0 (0)  
 Black 147 (53) 84 (56) 5 (56)   53 (47) 5 (83)  
 Hispanic 5 (2) 4 (3) 1 (11)   0 (0) 0 (0)  
 Other/unknown 5 (2) 2 (1) 1(11)   1 (1) 1 (17)  
CD4 countb     0.004    0.18
 <200 112 (40) 59 (39) 8 (89)   40 (36) 5 (83)  
 200–500 86 (31) 47 (31) 1 (11)   37 (33) 1 (17)  
 >500 69 (25) 39 (26) 0 (0)   30 (27) 0 (0)  
HIV viral loadc     0.54    0.04
 <200 154 (55) 89 (59) 4 (44)   60 (54) 1 (17)  
 200–1000 10 (4) 7 (5) 0 (0)   2 (2) 1 (17)  
 >1000 103 (37) 49 (32) 5 (56)   45 (40) 4 (66)  
Hepatitis B co-infectiond     0.47    0.21
 Chronic infection 59 (21) 15 (10) 2 (22)   15 (13) 1 (17)  
 Exposure and clearance 33 (12) 35 (23) 1 (11)   20 (18) 3 (50)  
 No exposure or infection 162 (58) 88 (58) 5 (56)   67 (60) 2 (33)  
Hepatitis C co-infectione     0.58    1.00
 Chronic infection 16 (6) 31 (21) 1 (11)   18 (16) 1 (17)  
 Exposure and clearance 51 (18) 10 (7) 1 (11)   5 (4) 0 (0)  
 No exposure or infection 189 (68) 99 (66) 6 (67)   79 (71) 5 (83)  
  1. aIn our health system, subjects self-identify as male or female. This information is recorded in the electronic health record
  2. bTime Period 1: 154 had a CD4 cell count measured, Time Period 2: 113 had a CD4 cell count measured
  3. cTime Period 1: 154 had a HIV Viral Load measured, Time Period 2: 113 had a HIV Viral Load measured
  4. dTime Period 1: 146 had HBV serologies measured, Time Period 2: 108 had HBV serologies measured
  5. eTime Period 1: 148 had HCV serologies measured, Time Period 2: 108 had HCV serologies measured