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Total study duration n (%)
|
Subjects with Time Period 1 non IRIS-attributable hospitalization n (%)
|
Subjects with Time Period 1 IRIS-attributable hospitalization n (%)
|
p value
|
Subjects with Time Period 2 non IRIS-attributable hospitalization n (%)
|
Subjects with Time Period 2 IRIS-attributable hospitalization n (%)
|
p value
|
|---|
|
Total subjects
|
278
|
151
|
9
| |
112
|
6
| |
|
Mean age
|
47.5
|
47.7
|
42.8
|
0.17
|
47.7
|
47.3
|
0.94
|
|
Sexa
| | | |
0.73
| | |
0.66
|
|
Male
|
192 (69)
|
105 (70)
|
7 (78)
| |
75 (67)
|
5 (83)
| |
|
Female
|
86 (31)
|
46 (30)
|
2 (22)
| |
37 (33)
|
1 (17)
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|
Race/ethnicity
| | | |
0.08
| | |
0.008
|
|
White
|
121 (44)
|
61 (40)
|
2 (22)
| |
58 (52)
|
0 (0)
| |
|
Black
|
147 (53)
|
84 (56)
|
5 (56)
| |
53 (47)
|
5 (83)
| |
|
Hispanic
|
5 (2)
|
4 (3)
|
1 (11)
| |
0 (0)
|
0 (0)
| |
|
Other/unknown
|
5 (2)
|
2 (1)
|
1(11)
| |
1 (1)
|
1 (17)
| |
|
CD4 countb
| | | |
0.004
| | |
0.18
|
|
<200
|
112 (40)
|
59 (39)
|
8 (89)
| |
40 (36)
|
5 (83)
| |
|
200–500
|
86 (31)
|
47 (31)
|
1 (11)
| |
37 (33)
|
1 (17)
| |
|
>500
|
69 (25)
|
39 (26)
|
0 (0)
| |
30 (27)
|
0 (0)
| |
|
HIV viral loadc
| | | |
0.54
| | |
0.04
|
|
<200
|
154 (55)
|
89 (59)
|
4 (44)
| |
60 (54)
|
1 (17)
| |
|
200–1000
|
10 (4)
|
7 (5)
|
0 (0)
| |
2 (2)
|
1 (17)
| |
|
>1000
|
103 (37)
|
49 (32)
|
5 (56)
| |
45 (40)
|
4 (66)
| |
|
Hepatitis B co-infectiond
| | | |
0.47
| | |
0.21
|
|
Chronic infection
|
59 (21)
|
15 (10)
|
2 (22)
| |
15 (13)
|
1 (17)
| |
|
Exposure and clearance
|
33 (12)
|
35 (23)
|
1 (11)
| |
20 (18)
|
3 (50)
| |
|
No exposure or infection
|
162 (58)
|
88 (58)
|
5 (56)
| |
67 (60)
|
2 (33)
| |
|
Hepatitis C co-infectione
| | | |
0.58
| | |
1.00
|
|
Chronic infection
|
16 (6)
|
31 (21)
|
1 (11)
| |
18 (16)
|
1 (17)
| |
|
Exposure and clearance
|
51 (18)
|
10 (7)
|
1 (11)
| |
5 (4)
|
0 (0)
| |
|
No exposure or infection
|
189 (68)
|
99 (66)
|
6 (67)
| |
79 (71)
|
5 (83)
| |
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aIn our health system, subjects self-identify as male or female. This information is recorded in the electronic health record
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bTime Period 1: 154 had a CD4 cell count measured, Time Period 2: 113 had a CD4 cell count measured
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cTime Period 1: 154 had a HIV Viral Load measured, Time Period 2: 113 had a HIV Viral Load measured
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dTime Period 1: 146 had HBV serologies measured, Time Period 2: 108 had HBV serologies measured
-
eTime Period 1: 148 had HCV serologies measured, Time Period 2: 108 had HCV serologies measured